Focus on helping families understand and feel empowered to manage their medical conditions.
About Jesse T. Lyon, PA
Jesse T. Lyon, PA-C, is a physician associate specializing in endocrinology at Phoenix Children's. Jesse cares for children with pediatric endocrine conditions, including diabetes, thyroid disorders, puberty concerns and growth delays, as well as an interest in adrenal and pituitary disorders.
After earning a Bachelor of Science in Microbiology from The University of Arizona in Tucson, Jesse earned a Master of Physician Associate Studies from Le Moyne College in Syracuse, New York. He is certified as a physician associate by the National Commission on Certification of Physician Assistants.
In addition to his expertise in adult and pediatric endocrinology, Jesse has worked on inpatient and outpatient management teams.
Jesse enjoys spending his free time with his wife and children, traveling to new places.
Medical School / Education
(BS) The University of Arizona, Tucson, AZ
(MPAS) Le Moyne College, Syracuse, NY
Physician Assistant
National Commission on Certification of Physician Assistants (NCCPA)
Quality Improvement award, Phoenix Children's Quality Day
Patient Advocate of the Year Nominee, Phoenix Children's
Professional Affiliations
Board Member, American Society of Endocrine Physician Associates
"A Dashboard-Driven Methodology for Phenotyping High-Utilization Risk in Pediatric T1DM" American Diabetes Association (ADA) annual conference, 2026.
"The Social Architecture of Childhood T1DM: A 1.5 Year Longitudinal Analysis of How Socio-Environmental Instability Predicts Readmission" American Association of Clinical Endocrinologist (AACE) annual conference, 2026.
"Malignant Infantile Osteopetrosis Caused by Two Compound Heterozygous TCIRG1 Gene Variants" Pediatric Endocrine Society (PES) annual conference, 2025.
"A Novel Screening Approach for Cushing's Syndrome," Endocrine Practice. American Association of Clinical Endocrinologist (AACE) annual conference, 2022.
Phoenix Children's Hospital - Thomas Campus
1920 E. Cambridge Ave.
Rosenberg Plaza
Phoenix, AZ 85006
Rating & Reviews
We love the staff and doctor who takes care of our visits and answers our care questions
We adore Jesse Lyons, P.A.! He does an outstanding job for our family! I am grateful for his expertise, and approach to my daughter's care. We are truly blessed to have Jesse as a provider. Corrine is also a seamless fit with Jesse in tandem. We couldn't be more pleased or grateful.
Jesse Lyon is great!
Our provider and nutritionist was so amazing their excitement with my son's improvement helped my son with encouraging him to keep making healthy choices and stay on the path of healthy changes. Helped and encouraged me as a mom to see that what he is doing is working.
Thank you for the good job that you do.
Staff was great
We have been seeing the endocrinologist department for the last 4 year every 3 months or so, and this visit was by far the most incredible experience. The educator, and team were thorough, and listened to all of our concerns. Offered great suggestions and supported my son in ways we had not previously received. Jesse was well informed, addressed all concerns, was positive, and offered supportive options available, suggested additional resources and we came up with a plan that we all felt good about moving forward. I have never felt more heard, and supported from this department. Whatever has changed, it is for the better. It is noticeable and we will continue to be scheduling all future appointments with Jesse and his team. Sincerely, thank you.
The doctor and the diabetes educator, who joined us virtually, worked very well together. They both were extremely knowledgeable and willing to help.
I think the visit went extremely amazing. I loved how the doctor paid attention to everything my daughter said and any concerns that we had and explained everything to her really well. I think he was amazing. I think also the nutritionist was amazing as well. She was explaining everything really good and any concerns that we had. So it was just an amazing experience for me and my daughter. Thank you guys so much.
Dr. Jessi Lion and Nutritionist Heather are amazing
Very helpful and very understand.
great physician assistant! great visit.
Everything was great.
Both doctor and nurse very helpful