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Germ Cell Tumors (GCTs) in Children What are germ cell tumors in children? A type of cell that forms as a fetus (also called unborn baby or embryo) develops is called a germ cell. Germ cells are the cells that make the eggs (ova) in females and the sperm in males. Germ cell

Lupus What is lupus? Systemic lupus erythematosus (SLE or lupus) is an autoimmune disease that causes your body’s immune system to attack its own cells and tissues. It causes episodes of inflammation to various parts of the body. It can affect your joints, tendons, and skin. It

Warts What are warts? Warts are common skin growths. They can spread to other parts of the body and to other people by contact. Most warts go away with no treatment over a long time. There are many kinds of warts. The most common types of warts are: Common warts. These grow on

Coarctation of the Aorta (COA) in Children What is coarctation of the aorta in children? Coarctation of the aorta (COA) is a heart defect that is present at birth (congenital). It means that the aorta is narrower than it should be. The aorta is the large artery that carries

Depression What is depression? Depression is a whole-body illness. It involves the body, mood, and thoughts. Depression affects the way you eat and sleep. It also can affect the way you feel about yourself, the people around you, and other things. It's not the same as being

Intussusception in Children What is intussusception in children? Intussusception is a serious problem in the intestine. It occurs when 1 part of the intestine slides inside another part. The intestine then folds into itself like a telescope. This creates a blockage or obstruction

Down Syndrome (Trisomy 21) in Children What is Down syndrome in children? Down syndrome is a genetic disorder. It is also called trisomy 21. It includes certain birth defects, learning problems, and facial features. A child with Down syndrome also may have heart defects and

GERD (Gastroesophageal Reflux Disease) in Children What is GERD in children? GERD (gastroesophageal reflux disease) is a long-term (chronic) digestive disorder. It happens when stomach contents flow back up (reflux) into the food pipe (esophagus) and cause symptoms or problems

Autism Spectrum Disorder in Children What is autism spectrum disorder in children? Autism spectrum disorder (ASD) is a problem that affects a child’s nervous system and growth and development. It often shows up during a child’s first 3 years of life. Some children with ASD seem

Neuroblastoma What is neuroblastoma in children? Neuroblastoma is cancer that starts when immature nerve cells in the nervous system grow out of control. These cells are called neuroblasts. Over time, the out-of-control cells form a tumor. Neuroblastoma is the most common solid