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Kidney Failure What is kidney failure? Kidney failure happens when damage results in loss of normal kidney function. There are 2 types of kidney failure—acute and chronic. Acute kidney failure starts abruptly. It can sometimes be reversed. Chronic kidney failure progresses slowly

Birth Defects in Children What is a birth defect in a child? A birth defect (congenital anomaly) is a health problem or abnormal physical change that is present when a baby is born. Birth defects can be very mild, where the baby looks and acts like any other baby. Or birth

Mood Disorders in Teens What are mood disorders in teens? Mood disorders are a group of mental health problems. They are sometimes called affective disorders. These are the most common types: Major depression. A teen with this type has a depressed or irritable mood, along with

Osteosarcoma (Osteogenic Sarcoma) in Children What is osteosarcoma in children? Osteosarcoma is very rare, but it's the most common kind of bone cancer in children and teens. It's most common in teens and young adults. Osteosarcoma is cancer that starts in the bone. The cancer

Down Syndrome (Trisomy 21) in Children What is Down syndrome in children? Down syndrome is a genetic disorder. It is also called trisomy 21. It includes certain birth defects, learning problems, and facial features. A child with Down syndrome also may have heart defects and

Spina Bifida in Children What is spina bifida in children? Spina bifida is a condition present at birth (birth defect) when there are problems with the spine, spinal cord, and the surrounding nerves. It can cause part of the spinal cord and areas around it to form outside of the

Open Neural Tube Defects (ONTDs) in Children What are open neural tube defects in children? Open neural tube defects (ONTDs) are problems with the way the brain, spinal cord, or spine forms while a baby is growing in the pregnant person’s uterus. These problems occur in about 1

Neurocutaneous Syndromes in Children What are neurocutaneous syndromes in children? Neurocutaneous syndromes are disorders that affect the brain, spinal cord, organs, skin, and bones. The diseases are lifelong conditions that can cause tumors to grow in these areas. They can also

Sickle Cell Disease in Children What is sickle cell disease in children? Sickle cell disease (SCD) is a blood disorder that a child is born with. It's passed down through a parent’s genes. Children with SCD make an abnormal type of hemoglobin. This is the protein in red blood