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Congenital Heart Disease According to the American Heart Association, about 9 of every 1,000 babies born in the U.S. have a congenital heart defect. This is a problem that occurs as the baby's heart is developing during pregnancy, before the baby is born. Congenital heart defects

Germ Cell Tumors (GCTs) in Children What are germ cell tumors in children? A type of cell that forms as a fetus (also called unborn baby or embryo) develops is called a germ cell. Germ cells are the cells that make the eggs (ova) in females and the sperm in males. Germ cell

Imperforate Anus in Children What is imperforate anus in children? Imperforate anus is a problem that your child is born with. It happens when your child has a blocked or missing anus. The final part of the digestive tract is the rectum. The rectum collects and compacts the solid

Multiple Sclerosis and Pregnancy What is multiple sclerosis? Multiple sclerosis (MS) is a chronic disease of the central nervous system, which is made up of the brain and spinal cord. MS is unpredictable. The symptoms of MS can range from mild to disabling, such as losing the

Pulmonary Stenosis in Children What is pulmonary stenosis in children? Pulmonary stenosis is a birth defect of the heart (congenital). It can happen when the pulmonary valve doesn’t grow as it should in a baby during the first 8 weeks of pregnancy. The pulmonary valve connects

Atrioventricular (AV) Canal Defect in Children What is an atrioventricular canal defect in a child? An atrioventricular (AV) canal defect is a congenital heart defect. This means that your child is born with it. AV canal defect is a large hole in the center of the heart. It is

Astrocytoma in Children What is an astrocytoma in children? An astrocytoma is a type of brain tumor. A brain tumor is an abnormal growth of tissue in the brain. The brain is part of the central nervous system (CNS). The CNS also includes the spinal cord. The main parts of the

Tricuspid Atresia What is tricuspid atresia? Tricuspid atresia (TA) is a heart defect present at birth (congenital). It occurs when the tricuspid valve doesn’t form, or only partly forms. Normally the tricuspid valve is located between the right upper chamber (atrium) and the

Chiari Malformation Type I in Children What is a Chiari malformation in children? A Chiari malformation (CM) is a problem with how the brain sits in the skull. The brain normally sits fully inside the skull. With a Chiari malformation, the lower part of the brain (cerebellum)

Pulmonary Atresia What is pulmonary atresia? Pulmonary atresia (PA) is a heart defect. It happens when the baby's heart doesn’t form as it should in the uterus. This can happen during the first 8 weeks of pregnancy. PA is a problem with the opening of the pulmonary valve. This