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Lupus What is lupus? Systemic lupus erythematosus (SLE or lupus) is an autoimmune disease that causes your body’s immune system to attack its own cells and tissues. It causes episodes of inflammation to various parts of the body. It can affect your joints, tendons, and skin. It

Anorectal Malformation in Children What is an anorectal malformation in children? Anorectal malformations are birth defects, or problems that happen as an unborn baby is developing during pregnancy. With this defect, the anus and rectum don’t develop properly. They are the lower

Kidney Failure What is kidney failure? Kidney failure happens when damage results in loss of normal kidney function. There are 2 types of kidney failure—acute and chronic. Acute kidney failure starts abruptly. It can sometimes be reversed. Chronic kidney failure progresses slowly

HIV AIDS What is HIV/AIDS? The term AIDS refers to the most advanced stages of an infection caused by the human immunodeficiency virus (HIV). The current definition of AIDS includes: All HIV-infected people who have fewer than 200 CD4+ T cells (also called T4 cells). These cells

Allergy Overview What are allergies? Allergies are due to a problem with the body's immune system. Most allergic reactions happen when the immune system reacts to a false alarm. Normally the immune system attacks harmful things, such as viruses or bacteria. But sometimes it

Birth Defects in Children What is a birth defect in a child? A birth defect (congenital anomaly) is a health problem or abnormal physical change that is present when a baby is born. Birth defects can be very mild, where the baby looks and acts like any other baby. Or birth

Mood Disorders in Teens What are mood disorders in teens? Mood disorders are a group of mental health problems. They are sometimes called affective disorders. These are the most common types: Major depression. A teen with this type has a depressed or irritable mood, along with

Osteosarcoma (Osteogenic Sarcoma) in Children What is osteosarcoma in children? Osteosarcoma is very rare, but it's the most common kind of bone cancer in children and teens. It's most common in teens and young adults. Osteosarcoma is cancer that starts in the bone. The cancer

Down Syndrome (Trisomy 21) in Children What is Down syndrome in children? Down syndrome is a genetic disorder. It is also called trisomy 21. It includes certain birth defects, learning problems, and facial features. A child with Down syndrome also may have heart defects and

Atherosclerosis What is atherosclerosis? Atherosclerosis is thickening of the walls of the arteries. It is also known as hardening of the arteries. It is caused by a buildup of plaque in the inner lining of an artery. Plaque is made up of deposits of fatty substances, cholesterol