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Osteosarcoma (Osteogenic Sarcoma) in Children What is osteosarcoma in children? Osteosarcoma is very rare, but it's the most common kind of bone cancer in children and teens. It's most common in teens and young adults. Osteosarcoma is cancer that starts in the bone. The cancer

Mood Disorders in Teens What are mood disorders in teens? Mood disorders are a group of mental health problems. They are sometimes called affective disorders. These are the most common types: Major depression. A teen with this type has a depressed or irritable mood, along with

Astrocytoma in Children What is an astrocytoma in children? An astrocytoma is a type of brain tumor. A brain tumor is an abnormal growth of tissue in the brain. The brain is part of the central nervous system (CNS). The CNS also includes the spinal cord. The main parts of the

Down Syndrome (Trisomy 21) in Children What is Down syndrome in children? Down syndrome is a genetic disorder. It is also called trisomy 21. It includes certain birth defects, learning problems, and facial features. A child with Down syndrome also may have heart defects and

Neurocutaneous Syndromes in Children What are neurocutaneous syndromes in children? Neurocutaneous syndromes are disorders that affect the brain, spinal cord, organs, skin, and bones. The diseases are lifelong conditions that can cause tumors to grow in these areas. They can also

Ewing Sarcoma in Children What is Ewing sarcoma in children? Ewing sarcoma is a rare type of cancer. It can affect a person of any age but it’s most common between ages 10 and 20. It often grows in bone, but it can also grow in soft tissue that’s connected to the bone. This may

Acute Spinal Cord Injury What is an acute spinal cord injury (SCI)? The spinal cord is a bundle of nerves that carries signals between the brain and the rest of the body. Acute spinal cord injury (SCI) is due to a traumatic injury. The injury may cause a bruise (contusion)

Germ Cell Tumors (GCTs) in Children What are germ cell tumors in children? A type of cell that forms as a fetus (also called unborn baby or embryo) develops is called a germ cell. Germ cells are the cells that make the eggs (ova) in females and the sperm in males. Germ cell

Head Injury What is a head injury? A head injury is a broad term that describes many injuries that occur to the scalp, skull, brain, and underlying tissue and blood vessels in the head. Head injuries are also commonly referred to as brain injury, or traumatic brain injury (TBI)

Spina Bifida in Children What is spina bifida in children? Spina bifida is a condition present at birth (birth defect) when there are problems with the spine, spinal cord, and the surrounding nerves. It can cause part of the spinal cord and areas around it to form outside of the