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Rheumatic Fever What is rheumatic fever? Rheumatic fever is a complex disease that affects the joints, skin, heart, blood vessels, and brain. It happens mainly in children between the ages of 5 and 15. It's an autoimmune disease that occurs after an infection with strep

Scleroderma in Children What is scleroderma in children? Scleroderma is an ongoing (chronic) disease that causes abnormal growth of connective tissue. It can affect the joints, skin, cartilage, and internal organs. It is a rare degenerative disease and gets worse over time. There

Septic Arthritis (Infectious Arthritis) in Children What is septic arthritis in children? Septic arthritis is an infection in the joint fluid (synovial fluid) and joint tissues. It occurs more often in children than in adults. The infection usually reaches the joints through the

Megaloblastic Anemia in Children What is megaloblastic anemia in children? Anemia is a problem in which there are not enough red blood cells or hemoglobin. Hemoglobin is the part of red blood cells that carries oxygen throughout the body. In megaloblastic anemia, the bone marrow

Sickle Cell Disease in Children What is sickle cell disease in children? Sickle cell disease (SCD) is a blood disorder that a child is born with. It's passed down through a parent’s genes. Children with SCD make an abnormal type of hemoglobin. This is the protein in red blood

Alpha Thalassemia in Children What is alpha thalassemia in children? Alpha thalassemia is an inherited blood disorder. This means it is passed down through the parent's genes. It may cause anemia in their children. Anemia is low numbers of red blood cells or low hemoglobin level

Beta Thalassemia in Children What is beta thalassemia in children? Beta thalassemia is an inherited blood disorder. This means it's passed down through a parent’s genes. It's a form of anemia. Anemia is a low red blood cell or low hemoglobin level. Hemoglobin is part of red blood

Congenital Heart Disease According to the American Heart Association, about 9 of every 1,000 babies born in the U.S. have a congenital heart defect. This is a problem that occurs as the baby's heart is developing during pregnancy, before the baby is born. Congenital heart defects

Diaphragmatic Hernia in Children What is a diaphragmatic hernia in children? A diaphragmatic hernia is a birth defect that occurs in about 1 out of 2,500 newborns. It happens in a baby during pregnancy. In this condition, there's an opening in your baby's diaphragm. This is the

Gastroesophageal Reflux in Children What is gastroesophageal reflux in children? Gastroesophageal refers to the stomach and esophagus. The esophagus is the tube that connects the throat to the stomach. Reflux means to flow back or return. Reflux happens because the lower