Hypothalamic Hamartoma Center

Hypothalamic hamartomas are rare, benign (non-cancerous) tumor-like formation on the hypothalamus, the area at the base of the brain that controls the production and release of hormones by the pituitary gland.

These growths are associated with a severe form of childhood epilepsy that causes two distinctive types of unusual seizures. The first type is called gelastic seizures, which are characterized by involuntary laughing. The second type are called dacrystic seizures, which are characterized by involuntary crying. Although these seizures may appear as episodes of laughter or crying, they often leave the child feeling scared or out of control.

Due to their unique characteristics, gelastic and dacrystic seizures are sometimes go unrecognized, or undiagnosed, until other symptoms arise. This delay can have serious consequences, including severe neurocognitive impairments, intellectual disabilities, early-onset puberty and profound behavioral disorders.

The Hypothalamic Hamartoma Center at Barrow Neurological Institute at Phoenix Children's provides individualized treatment plans tailored specifically to each child’s needs. Our comprehensive, multidisciplinary program is dedicated to evaluating and treating pediatric patients with hypothalamic hamartomas.

We are at the forefront of innovative surgical treatments, including minimally invasive Laser Interstitial Thermal Therapy (LITT). This advanced technique allows for precise targeting of the tumor and promotes quicker recovery. As leaders in the field our team is recognized globally for its extensive experience in performing these highly specialized surgeries.

Beyond delivering cutting-edge treatment, our goal is to support the hypothalamic hamartoma community on a global scale. We are committed to advancing care through effective treatments, educational resources and pioneering research to enhance future care for patients with this rare condition.