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Medical Genetics: Types of Genetic Changes The human body has about 20,000 different genes in each cell. Genes are located on chromosomes, which are stick-shaped structures in the middle of the cell (nucleus). Each cell usually has 46 chromosomes grouped in 23 pairs. Each gene

Gastroesophageal Reflux in Children What is gastroesophageal reflux in children? Gastroesophageal refers to the stomach and esophagus. The esophagus is the tube that connects the throat to the stomach. Reflux means to flow back or return. Reflux happens because the lower

Tuberculosis (TB) in Children What is tuberculosis in children? Tuberculosis (TB) is an ongoing (chronic) infection caused by bacteria. It usually infects the lungs. But other organs such as the kidneys, spine, or brain may be affected. TB is most often spread through droplets

Allergy Overview What are allergies? Allergies are due to a problem with the body's immune system. Most allergic reactions happen when the immune system reacts to a false alarm. Normally the immune system attacks harmful things, such as viruses or bacteria. But sometimes it

Cancer Overview What is cancer? Cancer is an abnormal growth of cells. The whole body is made of cells that act and grow in controlled ways as the body needs them. Cells are controlled by genes. The genes in any cell in the body can be damaged. Then the cell can grow out of

Ataxia Telangiectasia (A-T) What is ataxia telangiectasia (A-T)? Ataxia telangiectasia is a rare childhood disease that affects the nervous system, immune system, and other body systems. It is an inherited disease. The symptoms of A-T often begin to show up by age 5. How to say

Overview of Kidney Disorders How do the kidneys work? The body takes nutrients from food and converts them to energy. After the body has used all the food components that it needs, waste products are left behind in the bowel and in the blood. The kidneys and urinary system help

Claudication What is claudication? Claudication is pain in your thigh, calf, or buttocks that happens when you walk. It can make you limp. It may be a symptom of peripheral artery disease (PAD). This is when narrowed or blocked arteries reduce the blood flow to your legs. At

Polycystic Ovary Syndrome (PCOS) What is polycystic ovary syndrome (PCOS)? Polycystic ovary syndrome (PCOS) is a set of symptoms caused by a problem with a woman’s hormones. It affects the ovaries. These are the small organs that store a woman’s eggs. But it can also affect the

Metabolic Syndrome What is metabolic syndrome? Metabolic syndrome is when you have 3 or more health problems that put you at higher risk for diabetes, heart disease, and stroke. It is also known as insulin resistance syndrome. It’s also called syndrome X. If you have metabolic