Clinical trials are research studies conducted by physicians, or other medical personnel, to evaluate safety and effectiveness of a particular intervention — typically a treatment, prevention or detection strategy for a disease. Participants receive high-quality hemotological care and will be among the first to benefit if a new approach is proven to work.

Current Hematology Studies

  • Biogen 998HB303: An Open-Label, Multicenter Evaluation of the Safety and Efficacy of Recombinant Coagulation Factor IX Fc Fusion Protein (rFIXFc; BIIB029) in the Prevention and Treatment of Bleeding in Previously Untreated Patients With Severe Hemophilia B
  • Baxter 855: A Phase 3 Prospective, Uncontrolled, Multicenter Study Evaluating Pharmacokinetics, Efficacy, Safety, and Immunogenicity of BAX 855 (Pegylated Full-Length Recombinant FVIII) in Previously Treated Pediatric Patients with Severe Hemophilia A
  • Bayer 14372: Multicenter, open-label, active-controlled, randomized study to evaluate the efficacy and safety of an age-and body weight-adjusted rivaroxaban regimen compared to standard of care in children with acute venous thromboembolism  
  • CDC Public Health Surveillance for Bleeding Disorders: Registry for Bleeding Disorders Surveillance
  • Grifols ITP: A multi-center, prospective, open-label, clinical trial to assess the safety and the efficacy of a new intravenous immune globulin (IGIV3I Grifols 10%) in patients with idiopathic (immune) thrombocytopenic purpura
  • Fall Risk Study: Identifying fall risk in patients with hemophilia
  • Kids-DOTT Study: Prospective Multi-Center Evaluation of the Duration of Therapy for Thrombosis in Children (the “Kids-DOTT” Trial
  • Leucine DBA: A Pilot, Phase I/II Study of the Amino Acid Leucine in the Treatment of Patients with Transfusion-Dependent Diamond Blackfan Anemia
  • Mast Sickle Cell Study: Evaluation of Purified Poloxamer 188 in Vaso-Occlusive Crisis of Sickle Cell Disease (EPIC): A Phase 3 Randomized, Double-Blind, Placebo-Controlled, Multicenter Clinical Trial of MST-188 (purified poloxamer 188) Injection in Subjects with Sickle Cell Disease Experiencing Vaso-Occlusive Crisis
  • My Life Our Future: A Hemophilia Genotyping Initiative Data and Sample Research Repository
  • Novo Nordisk NN7008-3809: Safety and Efficacy of turoctocog alfa in Prevention and Treatment of Bleeds in Paediatric Previously Untreated Patients with Haemophilia A
  • Novo Nordisk NN7088-3860: Efficacy and Safety of NNCC 0129-0000-1003 during Surgical Procedures in patients with Hemophilia A
  • Pyruvate Kinase Deficiency (PKD) Natural History Study

Studies Not Currently Enrolling New Patients

  • Biogen 9HB01EXT B-LONG: An Open-label, Multicenter Evaluation of the Long-Term Safety and Efficacy of Recombinant Human Coagulation Factor IX Fusion Protein (rFIXFc) in the Prevention and Treatment of Bleeding Episodes in Previously Treated Subjects With Hemophilia B
  • Novo Nordisk NN7088-3859: A Multi-national Trial Evaluating Safety and Efficacy, including Pharmacokinetics, of NNC 0129-0000-1003 when Administered for Treatment and Prophylaxis of Bleeding in Patients with Haemophilia A
  • Novo Nordisk NN7088-3885: A Multinational, Open-Label, Non-Controlled Trial on Safety, Efficacy and Pharmacokinetics of NNC 0129-0000-1003 in Previously Treated Paediatric Patients with Severe Haemophilia A